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Tekbiotech-Yeast and Phage Display CRO, Expert in Nano-body and Antibody Drug Development
  • Overcoming Tumor Heterogeneity and Drug Resistance: Rational Design Strategies for Bispecific Aptamers2026-10-27
    Bispecific aptamers bind two targets with one molecule, overcoming tumor heterogeneity and drug resistance. Explore rational design strategies from TekBiotech.
  • Stop Screening Aptamers the Old Way: The Decisive Advantage of Magnetic-Bead SELEX2026-10-22
    Over 70% of recent aptamer papers use magnetic beads. Here is why bead-based SELEX outperforms membrane SELEX — and how to design negative selection right.
  • After the Halo Fades: How Antibody Discovery Is Returning to Science — and to Systems2026-10-20
    Why therapeutic antibody discovery is shifting from animal immunization to standardized phage and yeast display platforms — and how to choose between them.
  • Nanobodies: How a 15 kDa Single-Domain Antibody Breaks Through the Limits of Conventional Therapy2026-10-15
    Nanobodies are 15 kDa single-domain antibodies (VHH) that improve tissue penetration and stability. Explore nanobody discovery strategies and engineering for therapy.\n
  • pH-Dependent Antibodies: An Elegant Strategy for Extending Half-Life and Enhancing Target Clearance2026-10-13
    pH-dependent antibodies extend half-life while accelerating target clearance. Learn the acid-switch mechanism, engineering strategies, and the Fc–FcRn affinity threshold.
  • Magnetic Beads: How Do They Make SELEX Technology Fast, Precise, and Reliable?2026-09-29
    Magnetic bead–based SELEX (MB-SELEX) offers far more than convenient separation—it makes negative and competitive selection programmable. \n
  • Empowering Precision Medicine: The "Magic Scissors" and "Master Strokes" of Antibody Engineering2026-09-24
    This article reviews the key antibody engineering and chemical modification strategies that overcome these limitations, including humanized and fully human antibodies, antibody fragments and miniaturization , antibody–drug conjugates (ADCs), PEGylation.
  • Humanization calculation method and structural feature analysis of nanobodies!2026-09-22
    Nanobody humanization is a key strategy for reducing the immunogenicity of camelid-derived VHH candidates and improving their compatibility with the human immune system.
  • From Cell Line to Purified Drug Substance: How Therapeutic Antibodies Are Manufactured in Mammalian Cells2026-09-17
    Therapeutic antibodies have become household names — from PD-1 inhibitors that fight cancer to TNF-α antagonists that treat autoimmune diseases. Almost all of them depend on a shared "factory": the mammalian cell.
  • Affibody Molecules: Structural Advantages and Application Prospects of Small Affinity Proteins in Precision Diagnostics and Therapy2026-09-15
    Affibody molecules are 6.5 kDa engineered affinity proteins for molecular imaging and targeted therapy. Taike Biotech provides phage display, screening, and one-stop development services.\n
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