Animal Immunization Technology Services-Tekbiotech-Yeast Display Service,Phage display technology

目录&服务

Inquiry and ordering

Name*
Phone*
Email*
Product*
Content*

Animal Immunization Technology Services

TekBiotech provides customers with high-quality animal immunization services, including camel immunization, alpaca immunization, llama immunization, sheep immunization (goats and sheep), rodent immunization (mice, rats, guinea pigs), rabbit immunization and cattle immunization. With about 10 years of immunization experience, we can provide customized solutions and experimental execution procedures for customers' immunization requirements. The company's core competitiveness lies in combining phage display (Phagepro Tech^®) and yeast display technology to achieve efficient screening of specific antibodies for customers in the future. In order to meet the application needs of antibody discovery and tumor target discovery for scientific research and pharmaceutical customers, in addition to conventional animal rooms, TekBiotech has built alpaca and camel immunization bases. Alpacas come from South America and other places, and the source of the germ lineage is clear. Through the company's nano-antibody discovery platform, TekBiotech can continuously obtain high-quality immune raw materials, and combine our company's mature phage display technology and yeast display technology platform to provide customers with high-affinity and low-immunogenic nano-antibody discovery services.

█ Animal Immunization Types

Animal Immunization-tekbiotech1.png

Alpaca Immunization

Camel Immunization

Cow Immunization

Goat Immunization

Rabbit Immunization

Mouse Immunization

To ensure service quality, TekBiotech provides a one-stop solution from immunization, library construction to antibody screening. This includes immunization of alpacas/camels/rheas with customer-specified antigens, collection and separation of PBMCs, construction of nanoantibody display libraries, and efficient screening through phage or yeast display technology and corresponding downstream activity verification. This comprehensive service can greatly shorten the antibody development cycle, while improving the quality and diversity of antibodies, and meet the diverse needs of customers in the development of antibody drugs and diagnostic reagents.

█ Service Flow of Animal Immunization Platform of TekBiotech

Animal Immunization-tekbiotech7.png

Figure1 Animal immunization (schematic diagram of camel-derived animals and PBMC separation service)

TekBiotech Routine Animal Immunization Schedule:

Process	Description	Date
Negative serum collection	Pre-immunization serum collection	***
One immunization	Animal immunization	***
Two immunizations	Animal immunization	***
Three immunizations	Animal immunization	***
Four immunizations	Animal immunization	***
Four immunizations serum collection	ELISA titer detection + serum/cell separation	***
Five immunizations	Animal immunization	***
Five immunizations serum collection	ELISA titer detection + serum/cell separation	***

█ Animal Immunization Platform Quality Standard (QC Standard)

-- For protein antigens or viral antigens, the ELISA serum titer is >10^5; for polypeptide antigen immunization titer (carrier protein coupling), the ELISA serum titer is >10^4

-- Immunization times 5-7 times

-- For isolated PBMC cells, you can choose cell freezing solution or Trizol lysis form at will to ensure that the main bands of 28S, 18S and 5S are clear

-- For serum purification projects, IgG purity>90%

█ Service Advantages

Rich experience in immunization, guaranteed animal

immunization titer

Clear immunization plan, serum titer determination meets the

standards of the Chinese Pharmacopoeia

Provide detailed immunization plan periodic table and

immunization plan

Animal Immunization Technology Services Frequently Asked Questions

Q: After receiving immunity, animals have weaker immune responses, insufficient antibody production, or poor immune efficacy.

A: Consider increasing the immune dose, frequency, or duration, using appropriate immune adjuvants (such as Freund's adjuvant) to enhance the immune effect, and selecting more suitable immune animal strains.
Q: Animals exhibit non-specific reactions, leading to interference with experimental results.

A: Choose purer antigens, prepare more diluted antigen solutions, control experimental conditions, and reduce the occurrence of non-specific reactions.
Q: Animals experience excessive immune responses during the immune process, leading to tissue damage or immune related diseases.

A: Control the dosage and frequency of immunity to avoid excessive stimulation of the immune system; Choose appropriate immune animal strains and avoid susceptible animals.
Q: Animals exhibit immune suppression, leading to suppressed immune responses.

A: Consider using immunostimulants (such as polyclonal antibodies) to relieve immunosuppression, or adjusting treatment plans to avoid the influence of immunosuppressive factors.

Q: After receiving immunity, animals have weaker immune responses, insufficient antibody production, or poor immune efficacy.

A: Consider increasing the immune dose, frequency, or duration, using appropriate immune adjuvants (such as Freund's adjuvant) to enhance the immune effect, and selecting more suitable immune animal strains.
Q: Animals exhibit non-specific reactions, leading to interference with experimental results.

A: Choose purer antigens, prepare more diluted antigen solutions, control experimental conditions, and reduce the occurrence of non-specific reactions.
Q: Animals experience excessive immune responses during the immune process, leading to tissue damage or immune related diseases.

A: Control the dosage and frequency of immunity to avoid excessive stimulation of the immune system; Choose appropriate immune animal strains and avoid susceptible animals.
Q: Animals exhibit immune suppression, leading to suppressed immune responses.

A: Consider using immunostimulants (such as polyclonal antibodies) to relieve immunosuppression, or adjusting treatment plans to avoid the influence of immunosuppressive factors.

Consult Now Animal Immunization Technology Services

Animal Immunization Technology Services

Recommended Services

Animal Immunization Technology Services Frequently Asked Questions

Q: After receiving immunity, animals have weaker immune responses, insufficient antibody production, or poor immune efficacy.

Q: Animals exhibit non-specific reactions, leading to interference with experimental results.

Q: Animals experience excessive immune responses during the immune process, leading to tissue damage or immune related diseases.

Q: Animals exhibit immune suppression, leading to suppressed immune responses.

Q: After receiving immunity, animals have weaker immune responses, insufficient antibody production, or poor immune efficacy.

Q: Animals exhibit non-specific reactions, leading to interference with experimental results.

Q: Animals experience excessive immune responses during the immune process, leading to tissue damage or immune related diseases.

Q: Animals exhibit immune suppression, leading to suppressed immune responses.

Consult Now Animal Immunization Technology Services