Alias
科研级 Cixutumumab ( 西妥木单抗 ), Anti-CD221 Recombinant Antibody, Research Grade Cixutumumab
Molecular Name
Cixutumumab
Applications
IF, IP, Neut, FuncS, ELISA, FC
Purity
≥95% as determined by SDS-PAGE
Buffer
Supplied in PBS, PH7.5
Target
IGF1R/CD221[Homo sapiens]
Sequence
Please contact our sales representative to learn more information about this reagents.
Background
Cixutumumab (IMC-A12) is a human monoclonal antibody for the treatment of solid tumors. It is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor (IGF-1R) with potential antineoplastic activity. Cixutumumab selectively binds to membrane-bound IGF-1R, thereby preventing the binding of the ligand IGF-1 and subsequent activation of PI3K/AKT signaling pathway.
Storage
该产品可在 2°C-8°C 下保存一个月,活性不会明显降低。在 -20°C 至 -80°C 下保存,可稳定保存十二个月。避免反复冻融,用冰袋运输。